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Biological activity of phenolic compounds from argentinean herbs infusions

机译:阿根廷草药浸膏中酚类化合物的生物活性

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摘要

Argentinean herbal infusions were studied for their beneficial biological properties and secondary metabolites content, such as phenolic compounds in order to find new natural products beneficial. The modifications of antihypertensive and antioxidant activities by the addition of commonly used additives (lemon, sugar and sweetener) were studied also. Ilex paraguaiensis infusion showed the highest concentration of phenolic compounds and flavonoid fraction, the supplementation with lemon juice increased the phenolic compound content. All infusion showed high DPPH radical scavenging assays and additives did not modify significantly this activity. The infusion of I. paraguaiensis presents the maximum viability reduction of Escherichia coli and Staphylococcus aureus and the herbs combination Lippia integrifolia-Ilex paraguaiensis was the most effective to reduce S. aureus and E.coli viability. The phenolic compounds concentration as well as the qualitative composition of each infusion plays an important role in the antimicrobial activity. Because the high correlation between the concentration of total phenolic compounds and antioxidant and antihypertensive activities, we can infer that the phenolic compounds are responsible for such activities. The results obtained allow us to propose the herbs studied as potential natural antioxidants and antihypertensive compounds that could be used in pharmaceutical and food industries.
机译:为了寻找有益的新天然产物,研究了阿根廷草药输液的有益生物特性和次生代谢产物含量,例如酚类化合物。还研究了通过添加常用的添加剂(柠檬,糖和甜味剂)对降压和抗氧化活性的影响。巴拉圭冬青浸出液中酚类化合物和类黄酮的含量最高,柠檬汁的添加增加了酚类化合物的含量。所有输注均显示高DPPH自由基清除测定,且添加剂并未显着改变该活性。输注巴拉圭大肠埃希菌能最大程度降低大肠杆菌和金黄色葡萄球菌的生存能力,而草药联合利普氏菌-巴拉圭伊利培里亚组合最有效地降低了金黄色葡萄球菌和大肠杆菌的生存能力。每次输注中的酚类化合物浓度和定性组成在抗菌活性中起着重要作用。由于总酚类化合物的浓度与抗氧化剂和降压活性之间的高度相关性,我们可以推断出酚类化合物是造成此类活性的原因。所获得的结果使我们能够提出被研究为可用于制药和食品工业的潜在天然抗氧化剂和降压化合物的草药。

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